There isn't a general settlement about precise pharmacological remedy regimens for uncomplicated NMS.
This medication is prescribed in your current ailment only. Never use it afterwards for another situation Until told to take action by your health care provider. Another medication may very well be vital in Individuals cases.
Existence-threatening respiration problems (respiratory melancholy). Promethazine Hydrochloride and Codeine Phosphate Oral Alternative may cause respiration challenges (respiratory despair) which can materialize Anytime throughout therapy and may lead to death. Your risk of respiratory challenges is greatest if you 1st commence using Promethazine Hydrochloride and Codeine Phosphate Oral Alternative, are using other medicines that could potentially cause respiratory troubles, have particular lung issues, are elderly or have specified other health problems.
Excessively significant dosages of antihistamines, which include promethazine hydrochloride, in pediatric patients may perhaps result in sudden Loss of life (see OVERDOSAGE). Hallucinations and convulsions have transpired with therapeutic doses and overdoses of promethazine hydrochloride in pediatric individuals. In pediatric sufferers who're acutely ill related to dehydration, There may be an elevated susceptibility to dystonias with the usage of promethazine HCl.
2) Position the mixture in a sealable bag, empty can, or other container to circumvent the drug from leaking or breaking away from a rubbish bag, or to eliminate in accordance with nearby state recommendations and/or polices.
Postmarketing situations of respiratory depression, which include fatalities, happen to be described with utilization of promethazine hydrochloride in pediatric sufferers below 2 a long time of age. A variety of body weight-based mostly doses of promethazine hydrochloride have resulted in respiratory depression in these people.
The following significant adverse reactions are explained, or described in bigger element, in other sections:
Though antihistamines are found to make fetal mortality in rodents, the pharmacological results of histamine during the rodent tend not to parallel All those in gentleman. There aren't any suitable and nicely-controlled scientific studies of promethazine in pregnant Females.
Drug interactions may modify how your remedies get the job done or increase your hazard for severe Negative effects. This doc would not include all feasible Promethazine codeine syrup drug interactions.
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Instruct nursing moms to speak to the newborn's medical doctor instantly should they recognize these indications and, if they cannot reach the doctor without delay, to go ahead and take little one to an emergency home or connect with 911 (or community emergency services).
Never flush remedies down the bathroom or pour them into a drain Unless of course instructed to do so. Properly discard this solution when it's expired or no longer required. Talk to your pharmacist or neighborhood waste disposal business.
Concentration–Adverse Reaction Associations There is a relationship among expanding codeine plasma concentration and rising frequency of dose- linked opioid adverse reactions which include nausea, vomiting, CNS consequences, and respiratory despair.
Drop off any unused narcotic medicine in a drug acquire-back again area at once. If you do not Use a drug just take-back again site near you, flush any unused narcotic drugs down the bathroom.